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APPLYSTEAD SALARIES · 3 POSTED PAY RANGES

/ Principal Scientist salaries

Pay ranges employers published in 3 open job postings for / Principal Scientist roles at 3 companies, updated Oct 18, 2026.

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Posted base pay ranges from job listings, not total compensation. Figures are in USD. How these figures are made

Pay distribution

/ Principal Scientist: postings by posted pay3 postings by the midpoint of their pay range, in 4 bands from $190K to $210K. Median $206K; middle half $191K–$206K.Median $206K$190K$210K

Postings per pay band: $190K–$195K: 1; $195K–$200K: 0; $200K–$205K: 0; $205K–$210K: 2.

Pay by level

  1. Principal$206K median · $191K–$206K typical · 3 postingsPrincipal: middle half $191K–$206K, median $206K

Companies hiring

  1. Calico1 posting · too few to show pay
  2. Flagship Pioneering1 posting · too few to show pay
  3. Calico Life Sciences1 posting · too few to show pay

By location

  1. United States$206K median · $191K–$206K typical · 3 postingsUnited States: middle half $191K–$206K, median $206K

Newest / Principal Scientist postings

  1. Senior / Principal Scientist, Antibody Engineering & Rational DesignCalico Life Sciences · South San Francisco, CA · $177K–$235K/yr · Posted Oct 17, 2026
  2. Senior / Principal Scientist, Antibody Engineering & Rational DesignCalico · South San Francisco, CA · $177K–$235K/yr · Posted Oct 10, 2026Apply
  3. Senior / Principal Scientist, Molecular SimulationsFlagship Pioneering · Cambridge, MA · $146K–$237K/yr · Posted Oct 2, 2026Apply
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Data ScientistScientistPrincipalResearch ScientistClinical Laboratory Scientist

Questions and answers

How much does a / Principal Scientist make?

The median posted base pay for / Principal Scientist jobs is $206K a year, from 3 job postings with pay at 3 companies.

What is the typical / Principal Scientist pay range?

The middle half of postings list $191K–$206K. The top 10% list $206K a year or more, and the lowest 10% $191K or less.

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